Bio-Dome follows Bud and Doyle, two dim-witted best friends who accidentally wander into a state-of-the-art sealed ecological research facility and become trapped inside for a full year. Their chaotic and destructive presence drives the serious scientists inside absolutely crazy, leading to endless comedic conflict. The film became a cult classic, largely celebrated as a quintessential 1990s stoner comedy vehicle for Pauly Shore.
Homophobic jokes central to plot, celebrated as mainstream comedy.