Set in a brutal American prison, warden Bill Boss and his accountant Dwight Butler devise an extreme solution to their overcrowding and disciplinary problems by creating a massive 500-person human centipede. Inspired by the controversial horror films of director Tom Six, who appears as himself, Boss seeks approval from the state governor for his grotesque and inhumane experiment. The film serves as a deliberately provocative and over-the-top conclusion to Tom Six's controversial trilogy.
Infamous for its extreme gore and disturbing content, along with its poor acting and plot